Endocrine Abstracts

Introduction: Isolated adrenocorticotropic hormone (ACTH) deficiency (IAD) is a rare disease, which is characterized by secondary adrenal insufficiency with low cortisol production, and normal secretion of pituitary hormones other than ACTH. Although it is known that QT prolongation is sometimes observed in patients with IAD, reports on IAD in which the QT interval was sufficiently prolonged to cause Torsades de Pointes (TdP) are rare. We described the case of a patient with I...

Introduction: It has been reported that primary aldosteronism(PA) is often associated with subclinical Cushing syndrome (SCS). In the present study, we investigated the frequency of SCS in subjects with PA.Method: Subjects included consecutive patients (n=43) who were diagnosed as PA between 2003 and 2011 in our institute. They were screened by plasma renin activity (PRA (ng/ml/h)) plasma aldosterone concentration (PAC (pg/mL)) ratio (ARR) above 2...